Open AccessBiomarkers of hypoxia, endothelial and circulatory dysfunction among climbers in Nepal with AMS and HAPE: a prospective case–control study
Author(s) -
Kevin R. Barker,
Andrea L. Conroy,
Michael Hawkes,
Holly Murphy,
Prativa Pandey,
Kevin C. Kain
Publication year - 2016
Publication title -
journal of travel medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.985
H-Index - 59
eISSN - 1708-8305
pISSN - 1195-1982
DOI - 10.1093/jtm/taw005
Subject(s) - medicine , hypoxia (environmental) , circulatory system , prospective cohort study , cardiology , oxygen , chemistry , organic chemistry
The mechanisms underlying acute mountain sickness (AMS) and high-altitude pulmonary edema (HAPE) are not fully understood. We hypothesized that regulators of endothelial function, circulatory homeostasis, hypoxia and cell stress contribute to the pathobiology of AMS and HAPE.
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