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Tolerance and humoral immune response to the yellow fever vaccine in sickle cell disease children treated with hydroxyurea: a multicentre prospective study
Author(s) -
Bérengère Koehl,
Camille Aupiais,
Nelly Schinckel,
Pierre Mornand,
MarieHélène Odièvre,
Assa Niakaté,
Valentine Brousse,
Ghislaine Ithier,
Florence Missud,
Laurent Holvoet,
Malika Benkerrou,
F. Sorge,
Albert Faye
Publication year - 2021
Publication title -
journal of travel medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.985
H-Index - 59
eISSN - 1708-8305
pISSN - 1195-1982
DOI - 10.1093/jtm/taab013
Subject(s) - medicine , vaccination , immunogenicity , adverse effect , yellow fever vaccine , immune system , antibody , immunology , yellow fever , virus
Sickle cell disease (SCD) children are frequent travellers to countries where yellow fever (YF) is endemic, but there are no data regarding the safety and immunogenicity of the vaccine in such children treated with hydroxyurea (HU). The main objective of this study was to compare the tolerance and immune response to YF vaccination in SCD children treated or not with HU.

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