Increasing Clindamycin and Trimethoprim-Sulfamethoxazole Resistance in Pediatric Staphylococcus aureus Infections | Zendy

Dina F Khamash | Zendy; Annie Voskertchian | Zendy; Pranita D. Tamma | Zendy; Ibukunoluwa Akinboyo | Zendy; Karen C. Carroll | Zendy; Aaron M. Milstone | Zendy

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Increasing Clindamycin and Trimethoprim-Sulfamethoxazole Resistance in Pediatric Staphylococcus aureus Infections

Author(s) -

Dina F Khamash,

Annie Voskertchian,

Pranita D. Tamma,

Ibukunoluwa Akinboyo,

Karen C. Carroll,

Aaron M. Milstone

Publication year - 2018

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/piy062

Subject(s) - medicine , clindamycin , trimethoprim , staphylococcus aureus , sulfamethoxazole , microbiology and biotechnology , methicillin resistant staphylococcus aureus , antibiotics , bacteria , biology , genetics

The epidemiology of Staphylococcus aureus infection in children is dynamic. We conducted a retrospective observational study on pediatric clinical cultures, performed between 2005 and 2017, that grew S aureus to determine temporal trends in antibiotic resistance. Although methicillin resistance declined, clindamycin and trimethoprim-sulfamethoxazole resistance increased significantly, especially among community-onset isolates.

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