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We compared acute gastroenteritis (AGE)-related hospitalization rates among children &lt;5 years of age during the pre-rotavirus vaccine (2000-2006) and post-rotavirus vaccine (2008-2013) periods to estimate national reductions in AGE-related hospitalizations and associated costs. We estimate that between 2008 and 2013, AGE-related hospitalizations declined by 382000, and $1.228 billion in medical costs were averted.

journal of the pediatric infectious diseases society

National Estimates of Reductions in Acute Gastroenteritis–Related Hospitalizations and Associated Costs in US Children After Implementation of Rotavirus Vaccines