Hepatic, Renal, Hematologic, and Inflammatory Markers in HIV-Infected Children on Long-term Suppressive Antiretroviral Therapy
Author(s) -
Ann J. Melvin,
Meredith G. Warshaw,
Alexandra Compagnucci,
Yacine Saïdi,
Linda Harrison,
Anna Turkova,
Gareth TudorWilliams
Publication year - 2017
Publication title -
journal of the pediatric infectious diseases society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 31
eISSN - 2048-7207
pISSN - 2048-7193
DOI - 10.1093/jpids/pix050
Subject(s) - medicine , ritonavir , efavirenz , lopinavir , interquartile range , creatinine , gastroenterology , immunology , viral load , antiretroviral therapy , human immunodeficiency virus (hiv)
Data on long-term toxicity of antiretroviral therapy (ART) in HIV-infected children are sparse. PENPACT-1 was an open-label trial in which HIV-infected children were assigned randomly to receive protease inhibitor (PI)- or nonnucleoside reverse-transcriptase inhibitor (NNRTI)-based ART.
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