Deformed Subcortical Structures Are Related to Past HIV Disease Severity in Youth With Perinatally Acquired HIV Infection | Zendy

C. Paula Lewisde los Angeles | Zendy; Kathryn I. Alpert | Zendy; Paige L. Williams | Zendy; Kathleen Malee | Zendy; Yanling Huo | Zendy; John G. Csernansky | Zendy; Ram Yogev | Zendy; Russell B. Van Dyke | Zendy; Elizabeth R. Sowell | Zendy; Lei Wang | Zendy

Open Access

Deformed Subcortical Structures Are Related to Past HIV Disease Severity in Youth With Perinatally Acquired HIV Infection

Author(s) -

C. Paula Lewisde los Angeles,

Kathryn I. Alpert,

Paige L. Williams,

Kathleen Malee,

Yanling Huo,

John G. Csernansky,

Ram Yogev,

Russell B. Van Dyke,

Elizabeth R. Sowell,

Lei Wang

Publication year - 2016

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/piw051

Subject(s) - medicine , human immunodeficiency virus (hiv) , antiretroviral therapy , cognition , disease , cognitive skill , young adult , pediatrics , immunology , viral load , psychiatry , pathology

Combination antiretroviral therapy has led to increased survival among youth with perinatally acquired HIV (PHIV). However, cognitive deficits continue to be common. Histopathological studies in adults have found HIV concentrated in subcortical structures, which are involved in sensory processing, movement, and higher-order cognition that emerges with development.

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