Evaluation of the New World Health Organization Case Definition of Severe Acute Respiratory Infection for Influenza Surveillance During the Peak Weeks of Two Influenza Seasons in Quebec, Canada | Zendy

Rachid Amini | Zendy; Rodica Gilca | Zendy; Monique Douville-Fradet | Zendy; Nicole Boulianne | Zendy; Gaston De Serres | Zendy

Open Access

Evaluation of the New World Health Organization Case Definition of Severe Acute Respiratory Infection for Influenza Surveillance During the Peak Weeks of Two Influenza Seasons in Quebec, Canada

Author(s) -

Rachid Amini,

Rodica Gilca,

Monique Douville-Fradet,

Nicole Boulianne,

Gaston De Serres

Publication year - 2016

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/piw044

Subject(s) - medicine , respiratory system , influenza season , intensive care medicine , respiratory infection , virology , emergency medicine , vaccination , influenza vaccine

During the peak of the 2012-2013 and 2014-2015 influenza seasons in Quebec, Canada, the sensitivity of the new World Health Organization (WHO) case definition of severe acute respiratory infection (SARI) in <5-year-old children was 65% for polymerase chain reaction-confirmed influenza and 79% for other respiratory viruses (ORVs), whereas its specificity and positive predictive value were approximately 2- and 4-fold lower for influenza than ORVs (25% vs 40% and 18% vs 76%, respectively). The use of the WHO SARI definition for influenza surveillance in children should be interpreted with caution according to the specific surveillance goals.

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