Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants | Zendy

Sylvia BeckerDreps | Zendy; Wan Suk Choi | Zendy; Lisa Stamper | Zendy; Samuel Vilchez | Zendy; Daniel E. Velásquez | Zendy; SungSil Moon | Zendy; Michael G. Hudgens | Zendy; Baoming Jiang | Zendy; Sallie R. Permar | Zendy

Open Access

Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants

Author(s) -

Sylvia BeckerDreps,

Wan Suk Choi,

Lisa Stamper,

Samuel Vilchez,

Daniel E. Velásquez,

SungSil Moon,

Michael G. Hudgens,

Baoming Jiang,

Sallie R. Permar

Publication year - 2015

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/piv076

Subject(s) - medicine , immunogenicity , rotavirus vaccine , rotavirus , breast milk , innate immune system , immune system , immunology , breast feeding , virology , vaccination , breastfeeding , virus , pediatrics , biology , biochemistry

To better understand underlying causes of lower rotavirus vaccine effectiveness in low-middle income countries (LMICs), we measured innate antiviral factors in Nicaraguan mothers' milk and immune response to the first dose of the pentavalent rotavirus vaccine in corresponding infants. No relationship was found between concentrations of innate factors and rotavirus vaccine response.

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