Concomitant Medical Conditions and Therapies Preclude Accurate Classification of Children With Severe or Severe Complicated Clostridium difficile Infection | Zendy

Larry K. Kociolek | Zendy; S. J. Patel | Zendy; Stanford T. Shulman | Zendy; Dale N. Gerding | Zendy

Open Access

Concomitant Medical Conditions and Therapies Preclude Accurate Classification of Children With Severe or Severe Complicated Clostridium difficile Infection

Author(s) -

Larry K. Kociolek,

S. J. Patel,

Stanford T. Shulman,

Dale N. Gerding

Publication year - 2014

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/piu121

Subject(s) - medicine , concomitant , clostridium difficile , cohort , intensive care medicine , retrospective cohort study , pediatrics , antibiotics , microbiology and biotechnology , biology

Severe and severe complicated Clostridium difficile infections (SCDI/SCCDI) were retrospectively assessed in a pediatric cohort. Underlying medical conditions and concomitant medical therapy preclude accurate classification of children with SCDI/SCCDI, using current CDI severity definitions. Revised CDI definitions in children should focus on more objective, age-appropriate, and CDI-specific markers of severity.

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