Effect of HIV-1 Serostatus on the Prevalence of AsymptomaticPlasmodium falciparumParasitemia Among Children Less Than 5 Years of Age in Benin City, Nigeria | Zendy

Ikechukwu Okonkwo | Zendy; Michael O. Ibadin | Zendy; A I Omoigberale | Zendy; Wilson E. Sadoh | Zendy

Open Access

Effect of HIV-1 Serostatus on the Prevalence of AsymptomaticPlasmodium falciparumParasitemia Among Children Less Than 5 Years of Age in Benin City, Nigeria

Author(s) -

Ikechukwu Okonkwo,

Michael O. Ibadin,

A I Omoigberale,

Wilson E. Sadoh

Publication year - 2014

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/piu093

Subject(s) - parasitemia , serostatus , malaria , medicine , asymptomatic , plasmodium falciparum , immunology , interquartile range , odds ratio , immunosuppression , virology , pediatrics , viral load , human immunodeficiency virus (hiv)

Human immunodeficiency virus (HIV) infection and Plasmodium falciparum malaria are 2 of the gravest health threats in sub-Saharan Africa. Multiple repeat infections with the malaria parasite as seen in endemic areas are necessary to develop specific malaria immunity. HIV is an immunosuppressive virus and in children aged <5 years, development of malaria-specific immunity may be impaired and malaria parasite clearance in theory will be delayed; hence the predisposition to increased incidence of asymptomatic malaria or severe malaria. This cross-sectional study was carried out to examine associations between immunosuppression and asymptomatic malaria parasitemia (ASMP) in HIV-infected children aged <5 years in Benin City.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research