A 1-Year-Old WithMycobacterium tuberculosisEndocarditis With Mass Spectrometry Analysis of Cardiac Vegetation Composition: Table 1. | Zendy

Laura Sass | Zendy; Keegan Ziemba | Zendy; Elizabeth A. Heiser | Zendy; Clifford T. Mauriello | Zendy; A Werner | Zendy; Maria A. Aguiar | Zendy; Julius O. Nyalwidhe | Zendy; Kenji M. Cunnion | Zendy

Open Access

A 1-Year-Old WithMycobacterium tuberculosisEndocarditis With Mass Spectrometry Analysis of Cardiac Vegetation Composition: Table 1.

Author(s) -

Laura Sass,

Keegan Ziemba,

Elizabeth A. Heiser,

Clifford T. Mauriello,

A Werner,

Maria A. Aguiar,

Julius O. Nyalwidhe,

Kenji M. Cunnion

Publication year - 2014

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/piu087

Subject(s) - medicine , endocarditis , mycobacterium tuberculosis , mass spectrometry , immune system , microbiology and biotechnology , vegetation (pathology) , immunology , tuberculosis , pathology , biology , chromatography , chemistry

In this study, we report the first case of Mycobacterium tuberculosis endocarditis in an immunocompetent child born in the United States. Mass spectrometry of the vegetation identified coagulation, humoral immune proteins, neutrophil granule proteins, and histones. Few neutrophils on histopathology suggest that neutrophil extracellular traps may contribute to tuberculous endocardiac mass formation.

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