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The Group A Streptococcal Carrier State Reviewed: Still an Enigma
Author(s) -
Gregory P. DeMuri,
Ellen R. Wald
Publication year - 2014
Publication title -
journal of the pediatric infectious diseases society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 31
eISSN - 2048-7207
pISSN - 2048-7193
DOI - 10.1093/jpids/piu030
Subject(s) - medicine , intensive care medicine , group a , clinical trial , antimicrobial , epidemiology , streptococcal infections , immunology , microbiology and biotechnology , biology
Despite the common nature of group A streptococcal (GAS) infections, the carrier state of this organism is not well understood. In this article, we review the historical and recent research on the definition, epidemiology, and pathogenesis of the GAS carrier state. In addition, we outline trials of antimicrobial agents in the eradication of the carrier state and discuss indications for providing treatment to patients in the clinical setting.

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