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Variation in Risk of Hospital-Onset Clostridium difficile Infection Across -Lactam Antibiotics in Children With New-Onset Acute Lymphoblastic Leukemia
Author(s) -
Brian T. Fisher,
Julia Shaklee Sammons,
Yichen Li,
Peter de Blank,
Alix E. Seif,
Yung-Sung Huang,
Marko Kavčič,
Sarah B. Klieger,
T. B. Harris,
Kari Torp,
Douglas Patrick Rheam,
Ashish H. Shah,
Richard Aplenc
Publication year - 2014
Publication title -
journal of the pediatric infectious diseases society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 31
eISSN - 2048-7207
pISSN - 2048-7193
DOI - 10.1093/jpids/piu008
Subject(s) - medicine , cefepime , clostridium difficile , interquartile range , hazard ratio , antibiotics , ceftazidime , cohort , meropenem , pediatrics , confidence interval , antibiotic resistance , microbiology and biotechnology , genetics , imipenem , bacteria , pseudomonas aeruginosa , biology
Antibiotic exposure is common among children with leukemia. However, limited data exist regarding the risk of Clostridium difficile infection (CDI) across anti-pseudomonal β-lactam antibiotics commonly used for fever and neutropenia.

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