Susceptibility to Measles Among Perinatally HIV-Infected Adolescents and Young Adults
Author(s) -
Lawrence E. Morris,
Roberto Posada,
Carole J. Hickman,
Donald R. Latner,
T. A. Singh,
A. Rautenberg,
Jennifer Jao,
William J. Bellini,
Rhoda Sperling
Publication year - 2013
Publication title -
journal of the pediatric infectious diseases society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 31
eISSN - 2048-7207
pISSN - 2048-7193
DOI - 10.1093/jpids/pit054
Subject(s) - medicine , measles , pediatrics , human immunodeficiency virus (hiv) , young adult , virology , measles vaccine , vaccination , gerontology
Among our cohort of adolescents and young adults with perinatally acquired human immunodeficiency virus, few (17.6%) had measles protective antibodies by plaque reduction neutralization (PRN). Agreement was demonstrated between the commercial enzyme immunoassay and the PRN assay (K = 0.59 [95% confidence interval: 0.23-0.95]). Further studies are needed to understand the determinants of immunity in this population.
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