Treatment of Latent Tuberculosis Infection in Children | Zendy

Andrea T. Cruz | Zendy; Ashish Bajaj Ramez Ahmed | Zendy; Anna M. Mandalakas | Zendy; Jeffrey R. Starke | Zendy

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Treatment of Latent Tuberculosis Infection in Children

Author(s) -

Andrea T. Cruz,

Ashish Bajaj Ramez Ahmed,

Anna M. Mandalakas,

Jeffrey R. Starke

Publication year - 2013

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/pit030

Subject(s) - rifapentine , isoniazid , medicine , latent tuberculosis , pyrazinamide , tuberculosis , mycobacterium tuberculosis , intensive care medicine , pathology

Treatment of latent tuberculosis infection (LTBI) is an effective way of preventing future cases of tuberculosis disease. We review pediatric and adult studies of LTBI treatment (isoniazid and rifampin monotherapy, isoniazid plus rifampin, isoniazid plus rifapentine, and rifampin plus pyrazinamide). Based upon this review and our pediatric experience, we can offer recommendations for routine (isoniazid) and alternative courses of therapy.

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