Effects of Rhinovirus Infection on Nasopharyngeal Bacterial Colonization in Infants With Wild or Variant Types of Mannose-Binding Lectin and Toll-Like Receptors 3 and 4
Author(s) -
Sinikka Karppinen,
Juho Vuovirta,
Qiushui He,
Matti Waris,
Ville Peltola
Publication year - 2013
Publication title -
journal of the pediatric infectious diseases society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 31
eISSN - 2048-7207
pISSN - 2048-7193
DOI - 10.1093/jpids/pit025
Subject(s) - rhinovirus , moraxella catarrhalis , mannan binding lectin , streptococcus pneumoniae , microbiology and biotechnology , biology , haemophilus influenzae , colonization , immunology , virology , medicine , virus , lectin , antibiotics
Development of respiratory tract infections is determined by interactions between viruses, bacteria, and the host innate immune response. We investigated the impact of natural rhinovirus infection on nasopharyngeal bacterial colonization in infants with or without gene polymorphisms of mannose-binding lectin (MBL) and Toll-like receptors (TLRs) 3 and 4.
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