Successful Use of Temocillin as Salvage Therapy for Cervical Osteomyelitis Secondary to Multidrug-Resistant Burkholderia cepacia | Zendy

Marcela Rodriguez | Zendy; Mark Nelson | Zendy; John E. Kelly | Zendy; Alexis Elward | Zendy; S Morley | Zendy

Open Access

Successful Use of Temocillin as Salvage Therapy for Cervical Osteomyelitis Secondary to Multidrug-Resistant Burkholderia cepacia

Author(s) -

Marcela Rodriguez,

Mark Nelson,

John E. Kelly,

Alexis Elward,

S Morley

Publication year - 2013

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/pis110

Subject(s) - medicine , meropenem , osteomyelitis , tazobactam , doxycycline , burkholderia , cystic fibrosis , piperacillin , piperacillin/tazobactam , multiple drug resistance , burkholderia cepacia complex , salvage therapy , surgery , antibiotics , microbiology and biotechnology , chemotherapy , antibiotic resistance , imipenem , pseudomonas aeruginosa , bacteria , biology , genetics

Infection with multidrug resistant Burkholderia cepacia presents a therapeutic challenge in patients with cystic fibrosis. In this study, we present a case of progressive cervical osteomyelitis secondary to B cepacia that failed surgical drainage and extended therapy with meropenem, piperacillin-tazobactam, doxycycline, and aminoglycosides. Temocillin (Negaban) was successfully used to clear the infection.

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