Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) Antibody Responses in Children With Multisystem Inflammatory Syndrome in Children (MIS-C) and Mild and Severe Coronavirus Disease 2019 (COVID-19) | Zendy

Elizabeth M. Anderson | Zendy; Caroline Diorio | Zendy; Eileen C. Goodwin | Zendy; Kevin O. McNerney | Zendy; Madison E. Weirick | Zendy; Sigrid Gouma | Zendy; Marcus J. Bolton | Zendy; Claudia P. Arevalo | Zendy; Julie Chase | Zendy; Philip Hicks | Zendy; Tomaz B. Manzoni | Zendy; Amy E. Baxter | Zendy; Kurt P. Andrea | Zendy; Chakkapong Burudpakdee | Zendy; Jessica H. Lee | Zendy; Laura A. Vella | Zendy; Sarah E. Henrickson | Zendy; Rebecca M. Harris | Zendy; E. John Wherry | Zendy; Paul Bates | Zendy; Hamid Bassiri | Zendy; Edward M. Behrens | Zendy; David T. Teachey | Zendy; Scott E. Hensley | Zendy

Open Access

Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) Antibody Responses in Children With Multisystem Inflammatory Syndrome in Children (MIS-C) and Mild and Severe Coronavirus Disease 2019 (COVID-19)

Author(s) -

Elizabeth M. Anderson,

Caroline Diorio,

Eileen C. Goodwin,

Kevin O. McNerney,

Madison E. Weirick,

Sigrid Gouma,

Marcus J. Bolton,

Claudia P. Arevalo,

Julie Chase,

Philip Hicks,

Tomaz B. Manzoni,

Amy E. Baxter,

Kurt P. Andrea,

Chakkapong Burudpakdee,

Jessica H. Lee,

Laura A. Vella,

Sarah E. Henrickson,

Rebecca M. Harris,

E. John Wherry,

Paul Bates,

Hamid Bassiri,

Edward M. Behrens,

David T. Teachey,

Scott E. Hensley

Publication year - 2020

Publication title -

journal of the pediatric infectious diseases society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.269

H-Index - 31

eISSN - 2048-7207

pISSN - 2048-7193

DOI - 10.1093/jpids/piaa161

Subject(s) - medicine , coronavirus , covid-19 , antibody , immunology , severe acute respiratory syndrome , severe acute respiratory syndrome coronavirus , respiratory system , disease , severity of illness , virology , infectious disease (medical specialty) , outbreak

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antibody responses in children remain poorly characterized. Here, we show that pediatric patients with multisystem inflammatory syndrome in children (MIS-C) possess higher SARS-CoV-2 spike immunoglobulin G (IgG) titers compared with those with severe coronavirus disease 2019, likely reflecting a longer time since the onset of infection in MIS-C patients.

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