Longitudinal Barriers to Thiopurine Adherence in Adolescents With Inflammatory Bowel Diseases | Zendy

Jill M. Plevinsky | Zendy; Andrea A. Wojtowicz | Zendy; Steve Miller | Zendy; Rachel Neff Greenley | Zendy

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Longitudinal Barriers to Thiopurine Adherence in Adolescents With Inflammatory Bowel Diseases

Author(s) -

Jill M. Plevinsky,

Andrea A. Wojtowicz,

Steve Miller,

Rachel Neff Greenley

Publication year - 2018

Publication title -

journal of pediatric psychology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 121

eISSN - 1465-735X

pISSN - 0146-8693

DOI - 10.1093/jpepsy/jsy062

Subject(s) - medicine , thiopurine methyltransferase , medication adherence , observational study , affect (linguistics) , generalized estimating equation , longitudinal study , inflammatory bowel diseases , inflammatory bowel disease , physical therapy , disease , psychology , statistics , mathematics , communication , pathology

Cross-sectionally, more adherence barriers are associated with lower medication adherence. However, little is known about longitudinal associations between adherence barriers and adherence. Among adolescents with inflammatory bowel diseases (IBD), this study examined both (1) how time-varying self-reported adherence barriers affect daily thiopurine adherence and (2) how adherence barriers at baseline affect daily thiopurine adherence over a six-month period.

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