Open AccessRisk of Congenital Malformations in Children Born Before Paternal Cancer
Author(s) -
Yahia Al-Jebari,
Lars Rylander,
Olof Ståhl,
Aleksander Giwercman
Publication year - 2018
Publication title -
jnci cancer spectrum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.345
H-Index - 10
ISSN - 2515-5091
DOI - 10.1093/jncics/pky027
Subject(s) - medicine , congenital malformations , pediatrics , pregnancy , genetics , biology
The association between paternal cancer and risk of malformations in the offspring is not solely due to mutagenic effects of cancer therapy. The increase in prevalence of birth anomalies among children of fathers with malignancy might be due to cancer per se or a common underlying paternal factor, for example, genomic instability.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom