Long-Term Ovarian Cancer Survival Associated With Mutation in BRCA1 or BRCA2
Author(s) -
Esther M. John,
Barry P. Rosen,
Joel Moody,
Tuya Pal,
Isabel Fan,
Patricia A. Shaw,
Harvey A. Risch,
Thomas A. Sellers,
Ping Sun,
Steven A. Narod
Publication year - 2012
Publication title -
jnci journal of the national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.797
H-Index - 356
eISSN - 1460-2105
pISSN - 0027-8874
DOI - 10.1093/jnci/djs494
Subject(s) - ovarian cancer , hazard ratio , medicine , oncology , brca mutation , brca2 protein , serous fluid , cancer , gynecology , survival analysis , survival rate , mutation , ovary , confidence interval , germline mutation , biology , genetics , gene
Studies have suggested that the 5-year survival of women with ovarian cancer and a BRCA1 or BRCA2 mutation is better than expected. We sought to evaluate the impact of carrying a BRCA1 or BRCA2 mutation on long-term survival of women after a diagnosis of invasive ovarian cancer.
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