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A Prospective Study of Plasma Adiponectin and Pancreatic Cancer Risk in Five US Cohorts
Author(s) -
Ying Bao,
Edward L. Giovannucci,
Peter Kraft,
Meir J. Stampfer,
Shuji Ogino,
Jing Ma,
Julie E. Buring,
Howard D. Sesso,
IMin Lee,
John Michael Gaziano,
Nader Rifai,
Michaël Pollak,
Barbara B. Cochrane,
Virginia Kaklamani,
Jennifer Lin,
JoAnn E. Manson,
Charles S. Fuchs,
Brian M. Wolpin
Publication year - 2012
Publication title -
jnci journal of the national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.797
H-Index - 356
eISSN - 1460-2105
pISSN - 0027-8874
DOI - 10.1093/jnci/djs474
Subject(s) - adiponectin , medicine , prospective cohort study , odds ratio , body mass index , pancreatic cancer , case control study , insulin resistance , nested case control study , diabetes mellitus , endocrinology , oncology , cancer , insulin
The adipocyte-secreted hormone adiponectin has insulin-sensitizing and anti-inflammatory properties. Although development of pancreatic cancer is associated with states of insulin resistance and chronic inflammation, the mechanistic basis of the associations is poorly understood.

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