Neurokinin-1 Receptor Antagonists for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review
Author(s) -
Lucas Vieira dos Santos,
Fabrício Henrique Pereira De Souza,
André T. Brunetto,
André Deeke Sasse,
João Paulo da Silveira Nogueira Lima
Publication year - 2012
Publication title -
jnci journal of the national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.797
H-Index - 356
eISSN - 1460-2105
pISSN - 0027-8874
DOI - 10.1093/jnci/djs335
Subject(s) - antiemetic , nausea , vomiting , chemotherapy induced nausea and vomiting , aprepitant , medicine , tachykinin receptor 1 , chemotherapy , nk1 receptor antagonist , pharmacology , receptor , substance p , neuropeptide
The addition of neurokinin-1 receptor (NK1R) antagonists to antiemetic regimens has substantially reduced chemotherapy-induced nausea and vomiting (CINV). We sought to systematically review the overall impact of NK1R antagonists on CINV prevention.
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