An Epidemiological and Molecular Study of the Relationship Between Smoking, Risk of Nasopharyngeal Carcinoma, and Epstein–Barr Virus Activation | Zendy

Feng-Hua Xu | Zendy; Dan Xiong | Zendy; Ya-Fei Xu | Zendy; Su-Mei Cao | Zendy; Wen-Qiong Xue | Zendy; Hai-De Qin | Zendy; Wensheng Liu | Zendy; Jing-Yan Cao | Zendy; Ying Zhang | Zendy; Qi-Sheng Feng | Zendy; Li-Zhen Chen | Zendy; Man-Zhi Li | Zendy; ZhiWei Liu | Zendy; Qing Liu | Zendy; MingHuang Hong | Zendy; Yin Yao Shugart | Zendy; Yi-Xin Zeng | Zendy; MuSheng Zeng | Zendy; Wei-Hua Jia | Zendy

Open Access

An Epidemiological and Molecular Study of the Relationship Between Smoking, Risk of Nasopharyngeal Carcinoma, and Epstein–Barr Virus Activation

Author(s) -

Feng-Hua Xu,

Dan Xiong,

Ya-Fei Xu,

Su-Mei Cao,

Wen-Qiong Xue,

Hai-De Qin,

Wensheng Liu,

Jing-Yan Cao,

Ying Zhang,

Qi-Sheng Feng,

Li-Zhen Chen,

Man-Zhi Li,

ZhiWei Liu,

Qing Liu,

MingHuang Hong,

Yin Yao Shugart,

Yi-Xin Zeng,

MuSheng Zeng,

Wei-Hua Jia

Publication year - 2012

Publication title -

jnci journal of the national cancer institute

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.797

H-Index - 356

eISSN - 1460-2105

pISSN - 0027-8874

DOI - 10.1093/jnci/djs320

Subject(s) - nasopharyngeal carcinoma , lytic cycle , epstein–barr virus , virus , epidemiology , virology , antigen , antibody , immunology , medicine , herpesviridae , epstein–barr virus infection , gammaherpesvirinae , oncology , biology , viral disease , radiation therapy

Elevated levels of antibodies against antigens in the Epstein-Barr virus (EBV) lytic phase are important predictive markers for nasopharyngeal carcinoma (NPC) risk. Several lifestyle factors, including smoking, have also been associated with NPC risk. We hypothesized that some specific lifestyle factors induce transformation of EBV from the latent to the lytic stage and contribute to NPC occurrence.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research