Daily Aspirin Use and Cancer Mortality in a Large US Cohort
Author(s) -
Eric J. Jacobs,
Christina C. Newton,
Susan M. Gapstur,
Michael J. Thun
Publication year - 2012
Publication title -
jnci journal of the national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.797
H-Index - 356
eISSN - 1460-2105
pISSN - 0027-8874
DOI - 10.1093/jnci/djs318
Subject(s) - aspirin , medicine , relative risk , confidence interval , cancer , cohort , cohort study , cancer prevention , proportional hazards model , demography , surgery , sociology
A recent pooled analysis of randomized trials of daily aspirin for prevention of vascular events found a substantial reduction (relative risk [RR] = 0.63, 95% confidence interval [CI] = 0.49 to 0.82) in overall cancer mortality during follow-up occurring after 5 years on aspirin. However, the magnitude of the effect of daily aspirin use, particularly long-term use, on cancer mortality is uncertain.
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