Role of Interleukin 16 in Multiple Myeloma | Zendy

D. Atanackovic | Zendy; York Hildebrandt | Zendy; Julia Templin | Zendy; Yan Cao | Zendy; C. Keller | Zendy; Jens Panse | Zendy; Sabrina Meyer | Zendy; Henrike Reinhard | Zendy; Katrin Bartels | Zendy; Nesrine Lajmi | Zendy; Orhan Sezer | Zendy; A. R. Zander | Zendy; Andreas H. Marx | Zendy; Ria Uhlig | Zendy; Jozef Zustin | Zendy; Carsten Bokemeyer | Zendy; Nicolaus Kröger | Zendy

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Role of Interleukin 16 in Multiple Myeloma

Author(s) -

D. Atanackovic,

York Hildebrandt,

Julia Templin,

Yan Cao,

C. Keller,

Jens Panse,

Sabrina Meyer,

Henrike Reinhard,

Katrin Bartels,

Nesrine Lajmi,

Orhan Sezer,

A. R. Zander,

Andreas H. Marx,

Ria Uhlig,

Jozef Zustin,

Carsten Bokemeyer,

Nicolaus Kröger

Publication year - 2012

Publication title -

jnci journal of the national cancer institute

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.797

H-Index - 356

eISSN - 1460-2105

pISSN - 0027-8874

DOI - 10.1093/jnci/djs257

Subject(s) - bone marrow , multiple myeloma , stromal cell , flow cytometry , cancer research , plasma cell , microbiology and biotechnology , cytokine , biology , clone (java method) , cell culture , immunology , gene , genetics , biochemistry

Multiple myeloma is a malignancy characterized by the expansion of a plasma cell clone that localizes to the human bone marrow. Myeloma cells and bone marrow stromal cells produce soluble factors that promote the survival and progression of multiple myeloma. Interleukin 16 (IL-16) is involved in regulating the migration and proliferation of normal leukocytes. However, the role of IL-16 in human cancers, including multiple myeloma, is unclear.

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