Staging and Functional Characterization of Pheochromocytoma and Paraganglioma by 18F-Fluorodeoxyglucose (18F-FDG) Positron Emission Tomography | Zendy

Henri Timmers | Zendy; Clara C. Chen | Zendy; Jorge A. Carrasquillo | Zendy; Millie Whatley | Zendy; Alexander Ling | Zendy; Graeme Eisenhofer | Zendy; Kathryn S. King | Zendy; Jyotsna U. Rao | Zendy; Robert Wesley | Zendy; Karen T. Adams | Zendy; Karel Pacák | Zendy

Open Access

Staging and Functional Characterization of Pheochromocytoma and Paraganglioma by 18F-Fluorodeoxyglucose (18F-FDG) Positron Emission Tomography

Author(s) -

Henri Timmers,

Clara C. Chen,

Jorge A. Carrasquillo,

Millie Whatley,

Alexander Ling,

Graeme Eisenhofer,

Kathryn S. King,

Jyotsna U. Rao,

Robert Wesley,

Karen T. Adams,

Karel Pacák

Publication year - 2012

Publication title -

jnci journal of the national cancer institute

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.797

H-Index - 356

eISSN - 1460-2105

pISSN - 0027-8874

DOI - 10.1093/jnci/djs188

Subject(s) - pheochromocytoma , positron emission tomography , paraganglioma , magnetic resonance imaging , medicine , nuclear medicine , radiology , single photon emission computed tomography , adrenal medulla , fluorodeoxyglucose , emission computed tomography , pathology , catecholamine

Pheochromocytomas and paragangliomas (PPGLs) are rare tumors of the adrenal medulla and extra-adrenal sympathetic chromaffin tissues; their anatomical and functional imaging are critical to guiding treatment decisions. This study aimed to compare the sensitivity and specificity of (18)F-fluorodeoxyglucose positron emission tomography with computed tomography ((18)F-FDG PET/CT) for tumor localization and staging of PPGLs with that of conventional imaging by [(123)I]-metaiodobenzylguanidine single photon emission CT ((123)I-MIBG SPECT), CT, and magnetic resonance imaging (MRI).

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