Study Discovers Key Switch in Breast Cancer Metastases | Zendy

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Study Discovers Key Switch in Breast Cancer Metastases

Author(s) -

Mike Fillon

Publication year - 2012

Publication title -

jnci journal of the national cancer institute

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.797

H-Index - 356

eISSN - 1460-2105

pISSN - 0027-8874

DOI - 10.1093/jnci/djs150

Subject(s) - breast cancer , cytoskeleton , cytoplasm , cancer research , scaffold protein , key (lock) , cancer , metastasis , microbiology and biotechnology , medicine , biology , oncology , cell , signal transduction , genetics , ecology

according to a computational mechanical model. The cytoskeleton, present in all cells, is cellular scaffolding contained within the cytoplasm and made from protein. Previous studies have shown that elevated expression of p38 is associated with lower overall survival of patients with breast cancer. “Taken together, our results offer a detailed characterization of how p38 contributes to breast cancer progression.”

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