Open AccessHepatocellular Carcinoma and Other Liver Disease Among Greenlanders Chronically Infected with Hepatitis B Virus: A Population-Based Study
Author(s) -
Malene Landbo Børresen,
Anders Koch,
Robert J. Biggar,
Mikael Andersson,
Jan Wohlfahrt,
Karin Ladefoged,
Mads Melbye
Publication year - 2011
Publication title -
journal of the national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.797
H-Index - 356
eISSN - 1460-2105
pISSN - 0027-8874
DOI - 10.1093/jnci/djr405
Subject(s) - medicine , hepatocellular carcinoma , population , cancer registry , hepatitis b virus , poisson regression , incidence (geometry) , rate ratio , hepatitis b , cirrhosis , liver cancer , mortality rate , epidemiology , demography , immunology , virus , environmental health , physics , sociology , optics
In Greenland, the prevalence of hepatitis B surface antigen carriers, reflecting chronic hepatitis B virus (HBV) infection, is 5%-10%. However, the incidence of cirrhosis and hepatocellular carcinoma in this population has been reported to be low. We investigated this discrepancy in a large population-based cohort study.