Open AccessHistone Deacetylase 1 Gene Expression and Sensitization of Multidrug-Resistant Neuroblastoma Cell Lines to Cytotoxic Agents by Depsipeptide
Author(s) -
Nino Keshelava,
Elai Davicioni,
Zesheng Wan,
Lingyun Ji,
Richard Sposto,
Timothy J. Triche,
C. Patrick Reynolds
Publication year - 2007
Publication title -
jnci journal of the national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.797
H-Index - 356
eISSN - 1460-2105
pISSN - 0027-8874
DOI - 10.1093/jnci/djm044
Subject(s) - microbiology and biotechnology , biology , multiple drug resistance , neuroblastoma , daunorubicin , small interfering rna , histone deacetylase , histone deacetylase inhibitor , gene expression , cell culture , cancer research , gene , drug resistance , transfection , histone , immunology , biochemistry , leukemia , genetics
Genes that are overexpressed in multidrug-resistant neuroblastomas relative to drug-sensitive neuroblastomas may provide targets for modulating drug resistance.
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