Open AccessCombined Supplementation with Vitamin B-6 and Curcumin is Superior to Either Agent Alone in Suppressing Obesity-Promoted Colorectal Tumorigenesis in Mice
Author(s) -
Xian Wu,
Per Magne Ueland,
Jatin Roper,
Gar Yee Koh,
Liang Xu,
Jimmy W. Crott,
Ömer H Ilmaz,
Roderick T. Bronson,
Joel B Ason
Publication year - 2021
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxab320
Subject(s) - curcumin , vitamin , obesity , carcinogenesis , colorectal cancer , endocrinology , medicine , anti obesity , chemistry , pharmacology , cancer
Obesity increases the colorectal cancer risk, in part by elevating colonic proinflammatory cytokines. Curcumin (CUR) and supplemental vitamin B-6 each suppress colonic inflammation.
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