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Maternal Iron Deficiency Modulates Placental Transcriptome and Proteome in Mid-Gestation of Mouse Pregnancy
Author(s) -
Chang Cao,
Miguel A. Prado,
Liang Sun,
Shira Rockowitz,
Piotr Sliz,
João A. Paulo,
Daniel Finley,
Mark D. Fleming
Publication year - 2021
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxab005
Subject(s) - pregnancy , transcriptome , proteome , gestation , biology , placenta , fetus , physiology , endocrinology , medicine , bioinformatics , biochemistry , gene expression , genetics , gene
Maternal iron deficiency (ID) is associated with poor pregnancy and fetal outcomes. The effect is thought to be mediated by the placenta but there is no comprehensive assessment of placental responses to maternal ID. Additionally, whether the influence of maternal ID on the placenta differs by fetal sex is unknown.

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