Open AccessSupplemental Berberine in a High-Fat Diet Reduces Adiposity and Cardiac Dysfunction in Offspring of Mouse Dams with Gestational Diabetes Mellitus
Author(s) -
Laura Cole,
Ming Zhang,
Li Chen,
Genevieve C. Sparagna,
Marilyne Vandel,
Bo Xiang,
Ver W. Dolinsky,
Grant M. Hatch
Publication year - 2020
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxaa408
Subject(s) - offspring , endocrinology , medicine , gestational diabetes , insulin , berberine , diabetes mellitus , type 2 diabetes , pregnancy , biology , gestation , pharmacology , genetics
There are few evidence-based strategies to attenuate the risk of metabolic syndrome in offspring exposed to gestational diabetes mellitus (GDM). Berberine (BBR) is an isoquinoline alkaloid extracted from Chinese herbs and exhibits glucose lowering properties.
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