Open AccessActivation of the Farnesoid X Receptor (FXR) Suppresses Linoleic Acid-Induced Inflammation in the Large Yellow Croaker (Larimichthys crocea)
Author(s) -
Jianlong Du,
Qiang Chen,
Yongnan Li,
Xiaojun Xiang,
Wei Xu,
Kangsen Mai,
Qinghui Ai
Publication year - 2020
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxaa185
Subject(s) - farnesoid x receptor , proinflammatory cytokine , biology , inflammation , hek 293 cells , transfection , medicine , chenodeoxycholic acid , receptor , endocrinology , microbiology and biotechnology , reporter gene , nuclear receptor , biochemistry , gene expression , bile acid , gene , transcription factor , immunology
High linoleic acid (LA) intake leads to inflammation that adversely influences health in fish. However, whether the farnesoid X receptor (FXR) could be an effective target for regulating LA-induced inflammation remains unknown.
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