Open Accessʟ-Arginine Inhibits Apoptosis of Ovine Intestinal Epithelial Cells through the ʟ-Arginine–Nitric Oxide Pathway
Author(s) -
Hao Zhang,
Fangfang Zhao,
Along Peng,
Shuang Guo,
Mengzhi Wang,
Mabrouk Elsabagh,
Juan J. Loor,
Hongrong Wang
Publication year - 2020
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxaa133
Subject(s) - apoptosis , nitric oxide , nitric oxide synthase , reactive oxygen species , arginine , antioxidant , microbiology and biotechnology , superoxide dismutase , chemistry , endocrinology , biology , medicine , biochemistry , amino acid
In nonruminants, many of the biological roles of l-arginine (Arg) at the intestinal level are mediated through the Arg-nitric oxide (Arg-NO) pathway. Whether the Arg-NO pathway is involved in controlling the immune response and viability in ovine intestinal epithelial cells (IOECs) is unclear.
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