Open AccessHigh Dietary Fat and Selenium Concentrations Exert Tissue- and Glutathione Peroxidase 1–Dependent Impacts on Lipid Metabolism of Young-Adult Mice
Author(s) -
Zeping Zhao,
Jonggun Kim,
Xin Gen Lei
Publication year - 2020
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxaa130
Subject(s) - medicine , endocrinology , lipogenesis , adipose tissue , gpx1 , lipid metabolism , chemistry , glutathione peroxidase , metabolism , selenium , corn oil , biology , oxidative stress , superoxide dismutase , organic chemistry
Excessive dietary selenium (Se; 3 mg/kg) or fat (>25%) intakes and overproduction of glutathione peroxidase 1 (GPX1) adversely affect body lipid metabolism.
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