Open AccessSaponins in Garlic as Modifiers of the Risk of Cardiovascular Disease
Author(s) -
Hiromichi Matsuura
Publication year - 2001
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/131.3.1000s
Subject(s) - organosulfur compounds , allium , liliaceae , saponin , antifungal , steroid , allium sativum , traditional medicine , allicin , chemistry , biology , medicine , biochemistry , botany , microbiology and biotechnology , pathology , sulfur , alternative medicine , organic chemistry , hormone
Most chemical and biological studies about garlic have been conducted using organosulfur compounds. However, a variety of steroid saponins from garlic and related Allium species are being increasingly recognized for their importance in biological processes. This report demonstrates the isolation and structure determination of steroid saponins from garlic and aged garlic extract (AGE). In addition, the in vitro antifungal antitumor cytotoxicity and blood coagulability effects of steroid saponins from garlic and related Allium species are provided. Animal studies on the cholesterol-lowering effects of the saponin fractions from garlic are also summarized.
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