Open AccessDetermination of Insecticidal Effect (LC50and LC90) of Organic Fatty Acids Mixture (C8910+Silicone) AgainstAedes aegyptiandAedes albopictus(Diptera: Culicidae)
Author(s) -
James C. Dunford,
Aneika Falconer,
Laura N. Leite,
Robert A. Wirtz,
William G. Brogdon
Publication year - 2015
Publication title -
journal of medical entomology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 99
eISSN - 1938-2928
pISSN - 0022-2585
DOI - 10.1093/jme/tjv239
Subject(s) - aedes albopictus , aedes aegypti , chikungunya , biology , bioassay , aedes , dengue fever , vector (molecular biology) , mosquito control , pesticide , toxicology , larva , veterinary medicine , virology , ecology , biochemistry , immunology , medicine , gene , malaria , recombinant dna
Emerging and re-emerging vector-borne diseases such as chikungunya and dengue and associated Aedes vectors are expanding their historical ranges; thus, there is a need for the development of novel insecticides for use in vector control programs. The mosquito toxicity of a novel insecticide and repellent consisting of medium-chain carbon fatty acids (C8910) was examined. Determination of LC 50 and LC 90 was made against colony-reared Aedes aegypti (L.) and Aedes albopictus (Skuse) using probit analysis on mortality data generated by Centers for Disease Control and Prevention bottle bioassays. Six different concentrations of C8910 + silicone oil yielded an LC 50 of 160.3 µg a.i/bottle (147.6-182.7) and LC 90 of 282.8 (233.2-394.2) in Ae. aegypti; five concentrations yielded an LC 50 of 125.4 (116.1-137.6) and LC 90 of 192.5 (165.0-278.9) in Ae. albopictus. Further development of C8910 and similar compounds could provide vector control specialists novel insecticides for controlling insect disease vectors.
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