Open AccessAutophagy gets in on the regulatory act
Author(s) -
Steven K. Backues,
Daniel J. Klionsky
Publication year - 2010
Publication title -
journal of molecular cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.825
H-Index - 62
eISSN - 1674-2788
pISSN - 1759-4685
DOI - 10.1093/jmcb/mjq033
Subject(s) - autophagy , biology , microbiology and biotechnology , computational biology , genetics , apoptosis
Autophagy down-regulates the Wnt signal transduction pathway via targeted degradation of a key signaling protein. This may provide an explanation for autophagy's role in tumor suppression.
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