Open AccessThe Mighty Mice Prove Pluripotency for iPSCs
Author(s) -
Dong Pei
Publication year - 2010
Publication title -
journal of molecular cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.825
H-Index - 62
eISSN - 1674-2788
pISSN - 1759-4685
DOI - 10.1093/jmcb/mjp055
Subject(s) - induced pluripotent stem cell , embryonic stem cell , regenerative medicine , biology , microbiology and biotechnology , stem cell , genetics , gene
By injecting induced pluripotent stem cells (iPSCs) into tetraploid blastocysts to generate live pups, two groups in China demonstrated that the injected cells are as pluripotent as embryonic stem cells, i.e. capable of giving rise to every cell in the newborn mice. This achievement validates iPS technology for regenerative medicine.
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