Open AccessType I and Type II Pathways of Fas-mediated Apoptosis Are Differentially Controlled by XIAP
Author(s) -
Hao Zhou,
Tak W. Mak
Publication year - 2009
Publication title -
journal of molecular cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.825
H-Index - 62
eISSN - 1674-2788
pISSN - 1759-4685
DOI - 10.1093/jmcb/mjp034
Subject(s) - xiap , apoptosis , inhibitor of apoptosis , microbiology and biotechnology , inhibitor of apoptosis domain , biology , signal transduction , mechanism (biology) , genetics , chemistry , programmed cell death , caspase , philosophy , epistemology
The mechanism by which Fas activates the apoptotic pathway differs in so-called type I and type II cells. X chromosome-linked inhibitor of apoptosis protein has now been revealed as an important molecule that is differentially regulated in type I vs. type II cells.
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