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Adipocytes have been viewed as a space-filler in bone marrow for a long time. However, a recent study (Naveiras et al., 2009. Nature 460, 259-263) shows that adipocytes are microenvironmental components that suppress hematopoiesis under homeostatic and especially stressed conditions.

Shifting in Balance Between Osteogenesis and Adipogenesis Substantially Influences Hematopoiesis