Open AccessShifting in Balance Between Osteogenesis and Adipogenesis Substantially Influences Hematopoiesis
Author(s) -
Ryohichi Sugimura,
Linheng Li
Publication year - 2009
Publication title -
journal of molecular cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.825
H-Index - 62
eISSN - 1674-2788
pISSN - 1759-4685
DOI - 10.1093/jmcb/mjp030
Subject(s) - adipogenesis , haematopoiesis , bone marrow , homeostasis , balance (ability) , microbiology and biotechnology , adipose tissue , biology , stem cell , endocrinology , immunology , neuroscience
Adipocytes have been viewed as a space-filler in bone marrow for a long time. However, a recent study (Naveiras et al., 2009. Nature 460, 259-263) shows that adipocytes are microenvironmental components that suppress hematopoiesis under homeostatic and especially stressed conditions.
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