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A Little 'Help' from IL-21 During Persistent Viral Infection
Author(s) -
Dorian B. McGavern
Publication year - 2009
Publication title -
journal of molecular cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.825
H-Index - 62
eISSN - 1674-2788
pISSN - 1759-4685
DOI - 10.1093/jmcb/mjp021
Subject(s) - immune system , viral infection , biology , virology , immunology , microbiology and biotechnology , virus
Anti-viral CD4(+) T cells are required to orchestrate and sustain the activities of the adaptive immune system during a persistent viral infection. Three recent studies suggest that CD4(+) T cells accomplish this in part through the release of IL-21.

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