Do Substantia Nigra Dopaminergic Neurons Differentiate Between Reward and Punishment? | Zendy

Megan Frank | Zendy; D. James Surmeier | Zendy

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Do Substantia Nigra Dopaminergic Neurons Differentiate Between Reward and Punishment?

Author(s) -

Megan Frank,

D. James Surmeier

Publication year - 2009

Publication title -

journal of molecular cell biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.825

H-Index - 62

eISSN - 1674-2788

pISSN - 1759-4685

DOI - 10.1093/jmcb/mjp010

Subject(s) - substantia nigra , pars compacta , dopaminergic , neuroscience , punishment (psychology) , dopamine , psychology , midbrain , central nervous system , developmental psychology

The activity of dopaminergic neurons are thought to be increased by stimuli that predict reward and decreased by stimuli that predict aversive outcomes. Recent work by Matsumoto and Hikosaka challenges this model by asserting that stimuli associated with either rewarding or aversive outcomes increase the activity of dopaminergic neurons in the substantia nigra pars compacta.

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