Suicide with the Veterinary Drug Acepromazine | Zendy

Leena Stowell | Zendy

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Suicide with the Veterinary Drug Acepromazine

Author(s) -

Leena Stowell

Publication year - 1998

Publication title -

journal of analytical toxicology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.161

H-Index - 76

eISSN - 1945-2403

pISSN - 0146-4760

DOI - 10.1093/jat/22.2.166

Subject(s) - acepromazine , medicine , chromatography , pharmacology , chemistry , anesthesia , heart rate , blood pressure

A suicide case involving the veterinary drug acepromazine is described. After a single-step liquid alkaline extraction, acepromazine was identified in a chest-cavity blood sample using gas chromatography (GC) with nitrogen-phosphorus (NPD) and mass selective detectors. Acepromazine was then quantitated in the blood and other postmortem tissues by GC with NPD using chlorpromazine as the internal standard. Acepromazine concentrations in the chest-cavity blood, liver, brain, and bile were 0.6, 3.0, 0.4, and 6.5 micrograms/mL, respectively. The stomach contents contained a total of 2.5 mg acepromazine.

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