Open AccessA Fatal Case of Amlodipine Poisoning
Author(s) -
Simon H. Cosbey,
D.J.L. Carson
Publication year - 1997
Publication title -
journal of analytical toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.161
H-Index - 76
eISSN - 1945-2403
pISSN - 0146-4760
DOI - 10.1093/jat/21.3.221
Subject(s) - amlodipine , dihydropyridine , stomach , pharmacology , medicine , chemistry , calcium , blood pressure
A fatal case attributed to amlodipine intoxication is presented. The deceased was a 15-year-old girl who allegedly ingested 14 10-mg Istin tablets. Amlodipine concentration in peripheral blood was determined (2.7 mg/L) and was compared with published therapeutic and toxic data for amlodipine and some other dihydropyridine calcium channel-blocking agents. Amlodipine concentrations in liver, blood, and stomach contents were also determined.
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