CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia
Author(s) -
Ritu Banerjee
Publication year - 2021
Publication title -
jac-antimicrobial resistance
Language(s) - English
Resource type - Journals
ISSN - 2632-1823
DOI - 10.1093/jacamr/dlab152
Subject(s) - procalcitonin , medicine , intensive care medicine , pneumonia , community acquired pneumonia , respiratory tract infections , pediatrics , respiratory system , sepsis
Most clinical studies supporting procalcitonin (PCT)-guided management of lower respiratory tract infections have been performed in adults. There is a paucity of studies evaluating the clinical impact of PCT use in children and limited data informing age-appropriate PCT cut-offs; diagnostic accuracy in immunocompromised children; patient subgroups most likely to benefit from PCT testing; whether PCT adds value beyond available rapid molecular viral diagnostics; and optimal implementation strategies for PCT-guided treatment. At the present time there is little evidence to support routine use of PCT to aid management of paediatric pneumonia.
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