Large-scale genome mining allows identification of neutral polymorphisms and novel resistance mutations in genes involved in Candida albicans resistance to azoles and echinocandins | Zendy

Emilie Sitterlé | Zendy; Alix T. Coste | Zendy; Thomas Obadia | Zendy; Corinne Maufrais | Zendy; Murielle Chauvel | Zendy; Natacha Sertour | Zendy; Dominique Sanglard | Zendy; Anne Puel | Zendy; Christophe d’Enfert | Zendy; MarieElisabeth Bougnoux | Zendy

Open Access

Large-scale genome mining allows identification of neutral polymorphisms and novel resistance mutations in genes involved in Candida albicans resistance to azoles and echinocandins

Author(s) -

Emilie Sitterlé,

Alix T. Coste,

Thomas Obadia,

Corinne Maufrais,

Murielle Chauvel,

Natacha Sertour,

Dominique Sanglard,

Anne Puel,

Christophe d’Enfert,

MarieElisabeth Bougnoux

Publication year - 2019

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkz537

Subject(s) - biology , caspofungin , genetics , gene , point mutation , echinocandins , candida albicans , echinocandin , genome , azole , corpus albicans , drug resistance , mutation , fluconazole , microbiology and biotechnology , antifungal

The genome of Candida albicans displays significant polymorphism. Point mutations in genes involved in resistance to antifungals may either confer phenotypic resistance or be devoid of phenotypic consequences.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research