Candida albicans enhances meropenem tolerance of Pseudomonas aeruginosa in a dual-species biofilm | Zendy

Farhana Alam | Zendy; Dominic Catlow | Zendy; Alessandro Di Maio | Zendy; Jessica M. A. Blair | Zendy; Rebecca A. Hall | Zendy

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Candida albicans enhances meropenem tolerance of Pseudomonas aeruginosa in a dual-species biofilm

Author(s) -

Farhana Alam,

Dominic Catlow,

Alessandro Di Maio,

Jessica M. A. Blair,

Rebecca A. Hall

Publication year - 2019

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkz514

Subject(s) - biofilm , microbiology and biotechnology , pseudomonas aeruginosa , candida albicans , corpus albicans , multidrug tolerance , meropenem , mannan , biology , bacteria , antibiotics , chemistry , polysaccharide , antibiotic resistance , biochemistry , genetics

Pseudomonas aeruginosa is an opportunistic bacterium that infects the airways of cystic fibrosis patients, surfaces of surgical and burn wounds, and indwelling medical devices. Patients are prone to secondary fungal infections, with Candida albicans being commonly co-isolated with P. aeruginosa. Both P. aeruginosa and C. albicans are able to form extensive biofilms on the surfaces of mucosa and medical devices.

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