A 14 day esomeprazole- and amoxicillin-containing high-dose dual therapy regimen achieves a high eradication rate as first-line anti-Helicobacter pylori treatment in Taiwan: a prospective randomized trial | Zendy

WeiChen Tai | Zendy; ChihMing Liang | Zendy; ChungMou Kuo | Zendy; PaoYuan Huang | Zendy; ChengKun Wu | Zendy; ShihCheng Yang | Zendy; YuanHung Kuo | Zendy; MingTsung Lin | Zendy; ChenHsiang Lee | Zendy; ChienNing Hsu | Zendy; KengLiang Wu | Zendy; TsungHui Hu | Zendy; SengKee Chuah | Zendy

Open Access

A 14 day esomeprazole- and amoxicillin-containing high-dose dual therapy regimen achieves a high eradication rate as first-line anti-Helicobacter pylori treatment in Taiwan: a prospective randomized trial

Author(s) -

WeiChen Tai,

ChihMing Liang,

ChungMou Kuo,

PaoYuan Huang,

ChengKun Wu,

ShihCheng Yang,

YuanHung Kuo,

MingTsung Lin,

ChenHsiang Lee,

ChienNing Hsu,

KengLiang Wu,

TsungHui Hu,

SengKee Chuah

Publication year - 2019

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkz046

Subject(s) - esomeprazole , amoxicillin , medicine , helicobacter pylori , gastroenterology , clarithromycin , metronidazole , regimen , proton pump inhibitor , adverse effect , randomized controlled trial , antibacterial agent , intention to treat analysis , urea breath test , antibiotics , microbiology and biotechnology , helicobacter pylori infection , biology

The first-line eradication rate of standard triple therapy for Helicobacter pylori infection has declined to <80%, and alternative therapies with >90% success rates are needed. Inconsistent eradication rates were reported for proton pump inhibitor- and amoxicillin-containing high-dose dual therapy.

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